A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery
Wednesday, October 15, 2025
ASHG Posters: The Agony and The Ecstasy
ASHG is a huge meeting, probably the second largest I've ever attended after ASCO.  ASBMB is similar in size perhaps, though I think a hair smaller and definitely a bigger than ESHG.  And certainly multiple AGBTs in scale.  And that is crashing in on me now.
Tuesday, October 14, 2025
PacBio: $300 Genome Via Chemistry Update
ASHG is here in Boston, just down the street from Ginkgo's HQ.  I'm in a new role in Ginkgo Automation, trying to convince the NGS world that our automation platform is the bee's knees.  So excellent timing.  In advance of the meeting I was able to grab 30 minutes of PacBio CEO Christian Henry's time - last time I saw him he was fresh out of the legendary midnight AGBT  ILMN vs. PACB doubles beer pong match.  Christian gave me a heads up on some of the product news that hit the wires a bit earlier this morning. At the top of that is a new version of the core chemistry, SPRQ-Nx, which boosts yields 10-15% as well as the official launch of flowcell reuse.
Thursday, October 09, 2025
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