Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Tuesday, July 28, 2026

Dad Had Manuals, I Have An Agent

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My father was a very methodical person, and that particularly applied when he decided to purchase the second IBM PC clone to appear on the m...
Tuesday, July 21, 2026

Element's Curious Patentsieg

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Last week news broke that Element Biosciences had won a patent lawsuit against Illumina, and that it affected MiSeq.  MiSeq????  How did a p...
Monday, July 20, 2026

Fiber-Seq: Plasmids Model Chromosomes Well

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A recent publication in Molecular Cell involving Fiber-Seq caught my attention, though I've since discovered this preprinted over a yea...
Friday, July 10, 2026

The Simulator That Isn't There

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Okay, this is one of those cases where I kvetch about other people not having built the tools I want to use - perhaps a bit of a insufferabl...
Tuesday, July 07, 2026

Countable Labs Raises Funds, Heads to Clinic

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I caught up by teleconference recently with Countable Labs CEO Giovanna Prout, fresh off Countable Labs' $26M equity fundraising - a rou...
Sunday, June 28, 2026

Alex Hastie Returns to BioNano, Takes CSO Reins

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An interesting news item this week is that BioNano Genomics has appointed Alex Hastie as Chief Scientific Officer.  Hastie is an obvious cho...
2 comments:
Wednesday, June 24, 2026

E.coli Doesn't Like Diets Either, At Least Genomic Ones

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Another interesting preprint that fits several recent themes - genome minimization, discontinuation of products - comes from a Japanese grou...
Tuesday, June 23, 2026

Shredding Genomes: Establishing Plausible Deletability

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There's an interesting new preprint from Jay Shendure's lab which introduces the technique of Shred-Seq, which is a Cas3-driven app...
Thursday, June 18, 2026

The Commercial End for Fluidigm Technology?

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Last week brought news that Standard Biotools, which is what Fluidigm morphed into, is being acquired by Treeline Biosciences, a drug develo...
Saturday, June 13, 2026

Long Reads for Rare Diseases Hits New England Journal of Medicine

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Alexander Hoischen and colleagues have a brief piece in New England Journal of Medicine that published early this morning , in conjunction w...
1 comment:
Friday, June 12, 2026

Craig Venter Reflections: Building & Redesigning Genomes

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The last bit of Craig Venter's career a followed, often a bit green with envy, was his work to build genomes.  This all revolved around ...
Thursday, June 11, 2026

Craig Venter Reflections: Human Genome

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Few bombshells have hit genomics like the day in May 1998 when Craig Venter and Applied Biosystems announced he would be launching Celera Ge...
Wednesday, June 10, 2026

Craig Venter Reflections: Small Genomes

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In the early 1990s, Craig Venter left the NIH over disputes around the patenting of ESTs.  Investors backed him, but then William Haseltine ...
Tuesday, June 09, 2026

Craig Venter's Genomics Revolution: Setting the Stage

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I am overdue in getting back to my very personal review of how the recently passed J. Craig Venter made a huge impact on genomics science.  ...
Monday, June 01, 2026

FoG to Roll into Boston Seaport Wednesday & Thursday

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The Festival of Genomics, Biodata and AI - thankfully known as FoG and not FogBA or FogBDA - will be at the Boston convention center this W...
Sunday, May 31, 2026

London Calling: Long-Term R&D

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Now to run through the long term technical projections from Oxford Nanopore's Tech Talk.  Well, projection is probably not the correct w...
Saturday, May 30, 2026

London Calling: ONT's Near Term Launches

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I returned from London Calling 2026 much as I usually have - exhausted, more than a little hoarse, happy for discussions had and ruing conne...
2 comments:
Tuesday, May 19, 2026

London Calling 2026 Preview

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My series on Craig Venter is on a small pause since I didn't get it out before I arrived here in London for Oxford Nanopore's annual...
3 comments:
Tuesday, May 12, 2026

Personal Reflections on Craig Venter: Expressed Sequence Tags

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Venter's big Expressed Sequence Tag - soon known as ESTs -  paper came out in June during my final summer as an intern; I photocopied it...
1 comment:
Sunday, May 10, 2026

Personal Reflections on Craig Venter: Preface

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Craig Venter's sudden passing has triggered many writings about his life and work.  I'm overdue on my own personal reflections, and ...
1 comment:
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About Me

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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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