Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Tuesday, October 26, 2021

A Look at Two HiFi Polisher Preprints

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PacBio has made its reputation delivering very high accuracy long reads, which they have branded HiFi. These are based on their circular con...
Wednesday, August 04, 2021

PacBio Pulls Down Circulomics

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I was on vacation early this week when the news broke that PacBio has acquired HMW DNA solid phase extraction kit maker Circulomics -- the k...
Tuesday, July 20, 2021

PacBio Enters a Binding Agreement to Acquire Omniome

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Pacific Biosciences announced today that they are slurping up short read sequencer startup Omniome for around $800M.  Omniome has been devel...
11 comments:
Tuesday, June 29, 2021

ONT Sketches Paths to Long, Selective, Accurate Sequencing

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Some sort of summary of London Calling in this space is grossly overdue after getting caught by multiple work firedrills and then several re...
5 comments:
Wednesday, June 02, 2021

New Clinical Human Genome Speed Record

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I proposed last year that there should be a regular racing event for human genomics.  The only real competitor in is this interesting race ...
1 comment:
Tuesday, May 25, 2021

Matt Meselson Needs a Biographer!

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Yesterday was Matt Meselson's 91st birthday.  I have only met him a few times and he wouldn't know me from Adam, but he is a particu...
1 comment:
Thursday, May 20, 2021

My Latest London Calling Thoughts

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The title really says it -- London Calling has actually already begun and here I am pretending to write a "before the conference" ...
1 comment:
Sunday, April 25, 2021

GISAID Broken Down by Sequencing Hardware

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The GISAID database has been the workhorse for storing and distributing SARS-CoV-2 sequences during the COVID-19 pandemic and recently passe...
3 comments:
Tuesday, March 02, 2021

AGBT21: VizGen Unveils MERSCOPE

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More spatial profiling news coming in from AGBT -- Harvard spin-out VizGen is launching in the U.S. an instrument implementing MERFISH techn...
Monday, March 01, 2021

AGBT21: The LabRoots Presentation Platform is an Unmitigated Disaster

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Rant is ON!   I've been having an utterly miserable experience with the LabRoots conference software that AGBT is using for their virtua...

AGBT21: Rebus Esper for Spatial Sees Things You Wouldn't Believe

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My prediction that spatial would be a hot topic at AGBT was easy to make knowing I was sitting on embargoed news in the spatial space.  This...

AGBT21: A Few Pre-Conference Mutterings

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Getting some miscellanea out before AGBT21 starts later this morning
Sunday, February 28, 2021

AGBT 2021: A Spatial Foundation

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I'll call it now -- the big buzz at this year's AGBT will be around spatial profiling.  Trust me, it's not just a hunch.  The tw...
Saturday, February 27, 2021

PacBio With SoftBank's $900M: How Might TheyWork?

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Pacific Biosciences continued its roll of successful business development, snagging $900M from Japan's SoftBank two weeks ago.  Combined...
1 comment:
Friday, February 26, 2021

More Details on 10X's Sample Profiling Trident

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10X Genomics had an online event Wednesday called Xperience (as far as I could tell no Jimmy Hendrix music was used, a missed opportunity!) ...
Tuesday, February 09, 2021

Could I See Myself at J.P. Morgan?

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There's a question that others pop my way pretty much every year around J.P. Morgan: would I ever attend myself?  I'll confess it ne...
1 comment:
Monday, February 08, 2021

Why I Hated One Genapsys Slide

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I claimed in my Miscellanea piece that I was one post away from being done with J.P. Morgan -- oops, forgot I had drafted a minor screed on ...
1 comment:
Saturday, February 06, 2021

J.P. Morgan: Miscellania

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Before J.P. Morgan is truly a month ago I should clean up some loose ends as a penultimate post driven by this year's virtual conference...
Thursday, January 28, 2021

J.P.Morgan: NanoString

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Almost done with my J.P. Morgan summaries -- this will be the last focused on a specific company: nanoString.   They wish to emphasize that ...
Monday, January 25, 2021

J.P. Morgan: Genapsys

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Genapsys' J.P. Morgan presentation by CEO Hesaam Esfandyarpour focused on their story of delivering a compact sequencer based on electro...
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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