Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Friday, July 24, 2020

Two Pandemic-Related Programming Problems

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I will offer here two bioinformatics programming problems which I think are interesting, useful and should be approachable by an advanced un...
3 comments:
Monday, June 29, 2020

Virtual London Calling, Veritably Late, Part II: Platform Development

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Last time, I covered Oxford Nanopore LamPORE COVID-19 detection scheme .  London Calling was over a week ago, so the chance to scribble befo...
Wednesday, June 24, 2020

Virtual London Calling, Veritably Late Copy: Part I, LamPORE

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London Calling was last week, held online due to the pandemic.  My plans to attend in person were one of a myriad of travel arrangements upe...
2 comments:
Friday, May 29, 2020

Roche Expands Sequencing Nanopore Presence by Acquiring Stratos Genomics

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Ugh.  I let the month of April slip away without writing and now have almost let May do the same.  But some leftover euphoria from a huge ex...
3 comments:
Monday, March 30, 2020

One Gemini Celebrates Another

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One of most truly useless pieces of information lodged in my brain is my zodiac sign; not once in my life have I had any interest in it.  Bu...
Saturday, March 21, 2020

1918 Flu Pandemic & Popular Culture: Take Two

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My piece on the near amnesia in U.S. culture of the 1918-19 Influenza pandemic provoked a number of helpful comments, emails and conversati...
1 comment:
Tuesday, March 10, 2020

This Time ThermoFisher Catches QIAGEN

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This past fall there was a rumor that QIAGEN was being pursued by an acquirer, with the initial tip being scientific conglomerate ThermoFish...
3 comments:
Sunday, March 08, 2020

Post-AGBT: Miroculus

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AGBT ended over a week ago and I've been procrastinating ever since in going through notes and writing up companies.  First few days I h...
3 comments:
Saturday, March 07, 2020

Why Didn't the 1919 Flu Leave A Bigger Cultural Imprint?

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The still growing COVID-19 pandemic has reminded me of a question I've batted in my head a few times.  In 1918 and 1919 a global influen...
3 comments:
Wednesday, February 26, 2020

MGI Deconstructs the Sequencer

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At some fancy restaurants one can get a "deconstructed dish".  As I understand it, as I don't frequent such restaurants, a dec...
4 comments:
Saturday, February 22, 2020

CoolMPS Revealed

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Having s ummarized MGI's announcement they are launching into the U.S. market this spring and started digging into the performance char...
2 comments:

MGI Dual Drop of CoolMPS News Ahead of AGBT

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Friday morning I got excited because a p reprint showed up at BioRxiv detailing the CoolMPS sequencing technology from MGI (aka BGI aka Com...
3 comments:
Thursday, February 20, 2020

A Lazy Look at The Field of Sequencing Startups

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AGBT looms ahead of me next week which serves as impetus to let fly an idea I've had simmering for a while: to look at sequencing startu...
5 comments:
Tuesday, February 18, 2020

Skimming Seq

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My last post discussed BioJulia in the face of a challenge from the new Seq programming language.  Tonight I'm going to take a bit more ...
Thursday, February 13, 2020

A Short Master Class in Benchmarking

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There's a blog post on BioJulia.net that is well worth reading, even if you don't use Julia or I'd argue if you don't actual...
Tuesday, February 11, 2020

Sampling Current & Future Directions in PCR Diagnostics

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My qPCR explainer seems to have done relatively well, though it took some refinement after readers caught a number of errors.  The most emba...
2 comments:
Saturday, February 01, 2020

A qPCR (aka RT-PCR aka rRT-PCR) Explainer

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I've gotten in a number of Twitter threads and seen a lot of Quora questions about the qPCR test for the Wuhan coronavirus that I realiz...
7 comments:
Thursday, January 30, 2020

Can ONT Maintain Grip on Burgeoning Flowcell Herd?

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A notion dawned on me when I was mentally planning my write-up of the Nanopore Community Meetin g, but I decided to put off fleshing it out ...
4 comments:
Monday, January 27, 2020

An Ultimately Tufnellian Look At Oxford Nanopore R10.0 Homopolymer Performance

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Homopolymeric sequences have never been easy for any sequencing platform, but single molecule sequencers struggle the most with this.  Oxfor...
7 comments:
Sunday, January 26, 2020

UST Bets on TELL-Seq

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I've made a few references recently to TELL-Seq, both in my flawed analysis of BioNano Genomics (I missed a key business development in...
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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