Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Wednesday, February 26, 2020

MGI Deconstructs the Sequencer

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At some fancy restaurants one can get a "deconstructed dish".  As I understand it, as I don't frequent such restaurants, a dec...
4 comments:
Saturday, February 22, 2020

CoolMPS Revealed

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Having s ummarized MGI's announcement they are launching into the U.S. market this spring and started digging into the performance char...
2 comments:

MGI Dual Drop of CoolMPS News Ahead of AGBT

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Friday morning I got excited because a p reprint showed up at BioRxiv detailing the CoolMPS sequencing technology from MGI (aka BGI aka Com...
3 comments:
Thursday, February 20, 2020

A Lazy Look at The Field of Sequencing Startups

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AGBT looms ahead of me next week which serves as impetus to let fly an idea I've had simmering for a while: to look at sequencing startu...
5 comments:
Tuesday, February 18, 2020

Skimming Seq

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My last post discussed BioJulia in the face of a challenge from the new Seq programming language.  Tonight I'm going to take a bit more ...
Thursday, February 13, 2020

A Short Master Class in Benchmarking

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There's a blog post on BioJulia.net that is well worth reading, even if you don't use Julia or I'd argue if you don't actual...
Tuesday, February 11, 2020

Sampling Current & Future Directions in PCR Diagnostics

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My qPCR explainer seems to have done relatively well, though it took some refinement after readers caught a number of errors.  The most emba...
2 comments:
Saturday, February 01, 2020

A qPCR (aka RT-PCR aka rRT-PCR) Explainer

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I've gotten in a number of Twitter threads and seen a lot of Quora questions about the qPCR test for the Wuhan coronavirus that I realiz...
7 comments:
Thursday, January 30, 2020

Can ONT Maintain Grip on Burgeoning Flowcell Herd?

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A notion dawned on me when I was mentally planning my write-up of the Nanopore Community Meetin g, but I decided to put off fleshing it out ...
4 comments:
Monday, January 27, 2020

An Ultimately Tufnellian Look At Oxford Nanopore R10.0 Homopolymer Performance

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Homopolymeric sequences have never been easy for any sequencing platform, but single molecule sequencers struggle the most with this.  Oxfor...
7 comments:
Sunday, January 26, 2020

UST Bets on TELL-Seq

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I've made a few references recently to TELL-Seq, both in my flawed analysis of BioNano Genomics (I missed a key business development in...
Thursday, January 23, 2020

Can BioNano Genomics Map A Way Past Twin Perils?

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When playing with the structure of this piece in my mind, it occurred to me that Norman Maclean's thoughts about fly fishing apply just...
16 comments:
Wednesday, January 22, 2020

Genia: It's Alive!

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Once in a while I get the thrill of someone sending me a really good tip - that surge that comes with knowing that I know something that mos...
2 comments:
Sunday, January 19, 2020

10X Genomics Exits Genomes

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10X Genomics original product was a kit for generating linked reads from genomic DNA.  The idea had been kicking around for a while, partiti...
3 comments:
Friday, January 17, 2020

JPM20 Loose Ends: Agilent, ThermoFisher, 10X Genomics, NanoString - plus PacBio & ONT

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Time to close out  J.P. Morgan season with a grab bag of kvetches and kibbitzing on multiple 'omics companies that presented.  Much of t...
2 comments:
Tuesday, January 14, 2020

Bold Genapsys Talk at JPM20

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Genapsys' CEO  Hesaam Esfandyarpour   presented today at the JPM Morgan Conference and delivered an expansive vision of where the compa...
3 comments:
Monday, January 13, 2020

JPM20: Roche Links with Illumina On Diagnostics

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Another bit of Illumina news released at J.P. Morgan today is that Roche Diagnostics is partnering with Illumina.   The 15 year partnership ...
2 comments:

JPM20: Illumina Launches Super Resolution Instruments

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Illumina presented this morning at the J.P. Morgan Healthcare Conference ( presentation , slides & breakout ).  For us sequencing geeks...
1 comment:
Sunday, January 12, 2020

Is Illumina Vulnerable At The Bottom?

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According to both the FTC and CMA, Illumina holds a nearly complete monopoly on the sequencing market, with other players (Ion Torrent, Oxfo...
Thursday, January 09, 2020

Might Illumina Shave NovaSeq Run Times?

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I've had some people asking, either privately or via Twitter, what might come from Illumina next week at JP Morgan (8:30 am PST on Monda...
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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