Omics! Omics!

The 2017 Nanopore Community Meeting was over a week ago back in New York City, so I'm grossly overdue in cobbling together some observat...

I've been spending some time lately in an unfamiliar world: the eukaryotic section of NCBI's NR protein database.  I've been alm...

Apple launched the Macintosh computer with a famous television ad playing on the launch year, 1984. What emerged was what we now know as the...

Sometimes polony-style short read sequencing seems like old news.  The underlying technology has been commercially available for over a deca...

A comment was left on an early piece suggesting I comment on the recent AlphaGo paper and the possible applicability of this approach to bio...

The fact that tumors and their immediate environment is genetically heterogeneous has long been known, but tools for high-throughput assessm...

A theme for me in my six years on Starbase has been addressing the challenge of cost-effectively sequencing many small genomes.  While seque...

Well, here we go again.  Pacific Biosciences launched yet another patent lawsuit towards Oxford Nanopore at the end of September, and alread...

I had the singular honor and pleasure of speaking this past Monday at the Center for Disease Control and Prevention's Advanced Molecular...

LISP is one of the oldest computer languages and perhaps one of the most influential of the early ones.  Some of the other well-known Eisen...

I've been toying over a week with writing something based on an interesting Twitter discussion started by Dr. Laura Williams (@MicroWave...

High throughput sequencing of genomes is over twenty years old, which demanded the development of automated pipelines for annotating this da...

Last week's news contained a story sure to raise eyebrows.  A group of computer security researchers from the University of Washington c...

Over on Quora a common type of question is "Can I be a computational biologist if I am now an X".  Personally I take a very broad ...

When Oxford Nanopore announced their GridION X5 instrument in March , I and others attempted to parse the difference between the two pricing...

Tuesday's Boston Globe carried a piece originating from STAT news on an interesting natural product antibiotic, pleuromutilin.  A resea...

In my bit on " I'm not dead yet" technologies recently, I included large scale Sanger sequencing. That reflects to a large de...

I'm going to step outside the usual topic space here and cover an interesting but frustrating book I read partly on the flight to London...

In the closing talk of the pre-London Calling workshop, Hans Jansen had closed his presentation with a question whether at some future date ...

Okay, I'm desperately behind on writing up the external science from London Calling.  Not helpful that I claimed I would not only do so,...