Omics! Omics!

One of the frustrating side effects of outsourcing all your sequencing is that lack of connection to the actual machines.   Rarely have I go...

This morning was a solid block of meetings, but in a pause I checked my phone and saw the shocking headline: Roche Diagnostics had suddenly ...

A common approach for comparing sequencing platforms and assemblies is to report the consensus accuracy, just as for the platforms themselve...

Back in 2011,  I read and reviewed Dr. Siddhartha Mukherjee's book on the history of cancer therapy, The Emperor of All Maladies .  I l...

Reversible terminator nucleotides lie at the heart of sequencing-by-synthesis systems such as Illumina.  These nucleotides in their original...

The second and final day of Oxford Nanopore's New York User Meeting ran today.  I've again been mining tweets, since I wasn't on...

Oxford Nanopore officially kicked off its Community Meeting in New York City today; a training session took place yesterday.  Already there ...

Be prepared for another burst of Oxford Nanopore coverage; their annual Community Meeting in New York City begins on Thursday (perhaps whi...

In yesterday's post , I flagged a small factual error in Siddhartha Mukerherjee's The Gene.  I really liked Mukherjee's prior hi...

Kumar Thangdu's mission of prodding me has contributed to a bout of nostalgia for one of my graduate student rotation projects.  He aske...

Earlier this month the newsfeeds were abuzz over a new USB-stick style nucleic acid testing device. Based on technology from the United King...

Five years ago, the initial band of scientists at my current employer had just moved from the offices of our venture capitalist sponsor, Thi...

In the course of this blog, there are many topics I've thought about writing that I haven't touched.  Sometimes it is due to the pro...

It's been interesting revisiting a bunch of now ancient history of the Human Genome Project with the goal of exploring other possibiliti...

At the beginning of this series , I promised two alternative histories on the Human Genome Project.   Yesterday I explored a timeline in wh...

Okay, enough procrastination. I've outlined the general idea of counterfactuals and then obsessively detailed the generation of physica...

In this series leading to a pair of Human Genome Project alternative histories , I've been warming up with a trio of analyses of the tec...

I introduced this seven-part series with an exploration of the values and challenges of counterfactual histories .  Yesterday, I looked at ...

Yesterday's post explored the concept of alternative histories, or counterfactuals and laid out why they might be a useful way to think...

My new correspondent, Kumar Thangdu, has posed some challenging questions with regard to the Human Genome Project.  He's been good enou...