Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Thursday, March 31, 2016

Reflections on And The Band Played On

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Fellow blogger, colleague and science history buff Ash pointed out to me recently that Randy Shilt 's And The Band Played On  for Kindl...
Wednesday, March 30, 2016

Who Wants To Write A Review Article?

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Yes, this is a solicitation.  I'm on the Editorial Board of the journal Briefings in Bioinformatics ,.  I'm looking for authors who ...
3 comments:
Tuesday, March 29, 2016

At the Edge of The Cloud

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I've used cloud computing at Amazon Web Services (AWS) off-and-on now for over five years.  The cloud has all sorts of handy advantages ...
13 comments:
Friday, March 25, 2016

Selective sequencing: A Programming Opportunity!

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I ask a bit of indulgence from my regular readership for this piece, as I am going to explain a number of things in depth that probably will...
6 comments:
Friday, March 18, 2016

PacBio's big splash

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[18 March 2016 -- my original inclusion of the Pac Bio marketing image 6 years ago was claimed to be a DCMA violation -- I've simply rem...
1 comment:
Monday, March 14, 2016

A Mosquito ExAC?

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Okay, there's a scheme for a crazy big genomics project has bitten me, infecting my brain.  It's definitely not something I'm in...
3 comments:
Wednesday, March 09, 2016

Oxford's Riposte To Illumina Trade Action

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Along with the " No thanks, I've already got one " online session, the other big Oxford Nanopore news is the public release of...
6 comments:
Tuesday, March 08, 2016

Oxford's "No thanks, I've already got one"

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Oxford Nanopore today hosted a Google hangout titled " No thanks, I've already got one ".  Only this morning did it occur to...
8 comments:
Thursday, February 25, 2016

Digging into the Illumina Lawsuit vs. Oxford Nanopore

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Illumina's and University of Washington's filing of a patent lawsuit and related trade complaint against Oxford Nanopore made big ...
9 comments:
Wednesday, February 24, 2016

Amplification-free, library-free sequencing? NanoString wants to be It

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Perhaps the most unusual new technology to be unveiled at AGBT16 is NanoString's new approach to sequencing, which is in very early st...
Saturday, February 20, 2016

AGBT16 Storify Completion & Rate Limits

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AGBT16 ended a week ago, but for various reasons I'm just now catching up on my Storify project.  A vacation was in there but also so...
2 comments:
Friday, February 12, 2016

10X Launches Chromium (#agbt16)

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10X Genomics launched  their approach to obtaining long-range genomic information last year with a big financing and some exciting prelimina...
1 comment:

#AGBT16 Day 2: How is AGBT On Twitter Like Sequence Assembly?

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I spent a bunch of time yesterday going through the Tweets from AGBT.  For me personally it is a useful exercise, plus I'll have it as a...
4 comments:
Wednesday, February 10, 2016

AGBT Begins (with bonus Storify Jeremiad)

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Just finished my last Storify for tonight from AGBT16, and boy am I wondering how sustainable this will be.  The "problem", which ...

AGBT16 Preview (aka The Non-Attendee's Lament)

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AGBT16  starts this today but I'm again not there. The usual complex set of personal constraints (or imagined ones) kept my hat out of ...
1 comment:
Tuesday, February 09, 2016

Why do we purify DNA the way we do?

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An interesting conversation on Twitter on means for purifying DNA for PacBio and the risks of phenol-chloroform extractions restarted some...
Thursday, January 28, 2016

First on an occasional series on high school biology: Complexes

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TNG has biology this term, so I will be (at erratic intervals, of course) sometimes venturing my thoughts on the teaching of that specific s...
Friday, January 22, 2016

Does any analytical program really care about the order of paired end files?

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I was recently experimenting with C. Titus Brown and company's khmer package and hit an interesting little snag.  First, I had my usual...
5 comments:
Monday, January 18, 2016

Illumina's MiniSeq Giveaway

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This morning, Illumina announced a Scientific Challenge program as part of the launch of the MiniSeq sequencing instrument.  Three prizes ...
Tuesday, January 12, 2016

Illumina's Unveils Firefly

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Illumina third big announcement around JPM is to unveil Project Firefly , a semiconductor sequencer which will use existing SBS library prep...
8 comments:
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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