Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Monday, January 19, 2015

Cargo Cult Networking & Other LinkedIn Laments

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LinkedIn is a social media tool I find greatly flawed, but useful.  Part of the devil's pact one makes with LinkedIn is to receive great...
3 comments:
Sunday, January 18, 2015

JPM Wrap-Up:

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In this final installment of a series of reactions to news coming from the J.P. Morgan Conference, I'll cover an interesting complementa...
2 comments:
Wednesday, January 14, 2015

Illumina's Expanded Lineup

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In my J P Morgan predictions for sequencing platforms , I didn't do badly.  The only major player to make a platform announcement was Il...
7 comments:
Monday, January 12, 2015

2015: Another Year of Sequencing Evolution (not Revolution)?

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The J.P. Morgan Conference is firing up, and for the past few years that has meant big sequencing platform announcements -- HiSeq or Ion Pro...
4 comments:
Sunday, December 07, 2014

Druggability: An Underappreciated Issue in Translating the Human Genome Into Therapeutics

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I'm sorely guilty of neglecting this space, but a recent (and now storified ) Twitter conversation from Jonathan Eisen (@phylogenomics) ...
1 comment:
Tuesday, September 09, 2014

Reanalysis Lays Bare MinION Review's Spectacular Flaws

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I will confess that when our first MinION burn-in data for lambda came in & I threw a few aligners at it (after first getting my data ex...
3 comments:
Friday, September 05, 2014

Oxford Takes Some Flak, Fires Back

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A huge event in the genomics community this summer has been the Oxford Nanopore MinION Access Program (MAP), which has enabled a sizable but...
4 comments:
Monday, June 30, 2014

The good, bad & missing from Bio* libraries?

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As I mentioned recently, I've been exploring how I might use the emerging Julia language to solve problems.  While that requires a large...
3 comments:
Tuesday, June 24, 2014

After the New Yorker piece, what of disruptive innovation?

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I don't read a lot of books aimed at the MBA crowd, but one set I have liked, and sometimes cite here, are Clayton Christensen's on...
8 comments:
Tuesday, June 03, 2014

Dabbling with Julia

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As I've remarked before, I've done significant coding in a large number of languages over the last 35-or-so years.  I don't cons...
3 comments:
Wednesday, February 26, 2014

NGS Saves A Young Life

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One of the most electrifying talks at AGBT this year was given by Joe DeRisi of UCSF, who gave a brief intro on the difficulty of diagnosin...
15 comments:
Monday, February 24, 2014

A Sunset for Draft Genomes?

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The sun set during AGBT 2014 for a final time over a week ago.  The posters have long been down, and perhaps the liver enzyme levels of...
2 comments:
Thursday, February 13, 2014

How will you deal with GRCh38?

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I was foolishly attempting to catch up with Twitter last night during Valerie Schneider's AGBT talk last night on the new human referenc...
2 comments:
Thursday, January 16, 2014

Illumina's New Lineup

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Illumina made a brace of big hardware announcements at this week's J.P. Morgan conference, and Mick Watson has done a nice job of co...
11 comments:
Monday, January 13, 2014

Relearning Chemistry

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An evening ritual is to inquire what homework requires assistance, and at the beginning of the year it was a science worksheet as part of an...
2 comments:
Wednesday, January 01, 2014

Envisioning The Perfect Scaffolder

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Rather than make any New Year's resolutions of my own, which I would then feel guilty about not keeping, I've decided to make one fo...
3 comments:
Tuesday, December 31, 2013

Peering Through the Flowcell Glass, Darkly

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As 2013 draws to a close, I've decided to stick my neck out and make some predictions for 2014.  Perhaps I'll get lucky and a few wi...
3 comments:
Tuesday, December 17, 2013

Assembly Could Benefit From More Circular Reasoning

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It was very gratifying to get comments on my recent piece on a de novo assembly review from both a referee of the manuscript (the amazing H...
3 comments:
Sunday, December 15, 2013

Assembling a Review of a Review of Assembling

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A review on short-read de novo genome assembly appeared recently in PLoS Computational Biology, titled " Next-Generation Sequence Assem...
5 comments:
Friday, November 15, 2013

Did The Biochemists of Yore Know Morse Code?

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So, this piece is going to be mostly asking questions.  In one of the corners of my dream world I have a scientific historian on retainer, b...
4 comments:
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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