Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Thursday, May 26, 2011

Paying a Painful 75% Secrecy Tax

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In a post a while back , I mentioned that my Ion Torrent sequencing project was stalled because my service provider couldn't get some of...
16 comments:
Monday, May 23, 2011

MiSeq's First Light

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Someone was kind enough to send me a copy of a poster by Illumina reporting results from the MiSeq.  Now, to be very upfront, by someone I m...
2 comments:
Thursday, May 19, 2011

Forums: Open Beats Closed Hands Down

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Around the Internet, there are a number of communities in which scientists can swap useful information.   SEQAnswers is a very useful site ...
2 comments:
Saturday, May 14, 2011

Oh Would It Be Fun to Debug Strobe Sequencing!

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Through the course of a month, I easily sketch out (on average) a dozen plus experimental designs in the context of my day job.  Of course, ...
3 comments:
Friday, May 13, 2011

Blogger glitch

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Blogger experienced an outage which I found out about today.  This caused my last post to disappear; any posts or comments in a certain time...
1 comment:
Wednesday, May 11, 2011

Ion's Growing Pains

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A recent In Sequence article indicated that Ion Torrent is enjoying strong initial sales .  This bodes well for continued evolution and impr...
7 comments:
Sunday, May 08, 2011

Ion Torrent's Data Quality Is Pretty Good (and Better Than Ion Claims)

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One of the key questions around Ion Torrent, as with all new platforms, is what is the sequence data quality like.  Now, that can be a loade...
10 comments:
Saturday, May 07, 2011

Which numbers did I use this time?

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Noted screenwriter William Goldman's second memoir on the film industry is titled " Which Lie Did I Tell? ".  The title is not...
3 comments:
Monday, May 02, 2011

How Many More Machines will PacBio Sell This Year?

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Amongst last week's news is the item that P acific Biosciences has officially launched their SMRT sequencing platform .  I'd too eye...
3 comments:
Wednesday, April 13, 2011

Better Template Prep for Ion Announced

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One of the perceived weak points of the Ion Torrent, in contrast to the Illumina, has been the use of emulsion PCR for template preparation....
9 comments:
Tuesday, April 12, 2011

Vostok & Columbia

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It has hardly gone unreported in the media that today marks the 50th anniversary of the manned spaceflight and the 30th of the first space ...
Friday, April 08, 2011

Gnoteworthy But Gnot Gnoticed

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A commenter on yesterday's piece on Intelligent Biosystems scolded me on not mentioning GnuBio and said they had released data.  This h...
5 comments:

Another Low Cost Sequencer on the Horizon?

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An article in GenomeWeb's In Sequence (which, alas, requires a subscription for which I've never sprung) has a p iece on Intelligent...
2 comments:
Tuesday, April 05, 2011

Can we treat the kinase du jour?

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For the second time in just over a week, the Boston Globe Sunday was discussing protein kinases in the context of cancer.  A group from the ...
4 comments:
Wednesday, March 23, 2011

What might a PGM2 look like?

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The New England chapter of the Laboratory Robot Interest Group ( NE-LRIG ) had a nice meeting tonight over at Astra Zeneca's beautiful W...
4 comments:
Tuesday, March 22, 2011

What's On Your Cheat Sheet?

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After years of scribbling on a motley collection of pads, during my time at Infinity I've been nearly rigorous about using a single note...
3 comments:
Friday, March 18, 2011

My Noisy Neighbors

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My neighbors are up to their loud antics again; a really wild singles party. Fact of the matter is, I checked very carefully one evening be...
1 comment:
Tuesday, March 08, 2011

What will be the last Sanger genome?

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Even when I was finishing up as a graduate student, and only a few bacterial genomes had been published, one would periodically hear open sp...
4 comments:
Wednesday, March 02, 2011

Emulsion PCR: First Notes

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One theme in some of the comments on my Ion Torrent commentary has been around the limitations of emulsion PCR. Some have made rather bold...
12 comments:
Tuesday, March 01, 2011

When Will Life Technologies Get Serious About Their Grand Challenges?

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My recent run of posts on Ion Torrent certainly garnered a lot of comments, and it would be much less than honest to say that many of the c...
4 comments:
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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