Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Monday, December 20, 2010

Google's Ngram Viewer

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I've been playing off and on with Google's Ngram viewer since it was announced on Friday. This is the tool that enables you to gra...
3 comments:
Sunday, December 19, 2010

Bone Marrow Registries of Contention, and the Future of Tissue Typing?

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This summer I took TNG to the Portsmouth Air Show to enjoy viewing aerobatics and looking at some aircraft up close. As with many such even...
Friday, December 10, 2010

Is Pacific Biosciences Really Polaroid Genomics?

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The New England Journal of Medicine this week carries a paper from Harvard and Pacific Biosciences detailing the sequence of the Vibrio cho...
1 comment:
Friday, December 03, 2010

Arsenic and New Microbes

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Yesterday's announcement of a microbe which not only tolerates arsenic but actually appears to incorporate it in place of phosphorous ha...
4 comments:
Wednesday, November 03, 2010

Mild alleles in severe diseases: an opportunity for enlightenment

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Monday's Globe had a blurb about a book signing which re-kindled a previus interest of mine. The author, Michael Dana Kennedy , had qui...
1 comment:
Sunday, October 31, 2010

Plenty of Genomes are Still Fair Game for Sequencing

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I've been grossly neglecting this space for an entire month with only the usual excuses -- big work projects, a lot of reading, etc. No...
6 comments:
Tuesday, September 28, 2010

Scenes from the Cancer Personalized Medicine Wilderness

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I'm going to attempt to synthesize a number of thoughts which I've long pondered along with a bunch of news items I came across toda...
2 comments:
Tuesday, September 21, 2010

Review: The $1000 Genome

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Kevin Davies' "The $1000 Genome" deserves to be widely read. Readers of this space will not be surprised that there are a few...
2 comments:
Saturday, September 11, 2010

ARID1A A Fertile Ground for Mutations in Ovarian Clear Cell Carcinoma

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Although ovarian clear cell carcinoma does not respond well to conventional platinum–taxane chemotherapy for ovarian carcinoma, this remains...
2 comments:
Tuesday, August 31, 2010

Worse Could Be Better

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My eldest brother was in town recently on business & in our many discussions reminded me of the thought-provoking essay " The Rise ...
4 comments:
Sunday, August 29, 2010

Who has the lead in the $1K genome race?

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A former colleague and friend has asked over on a LinkedIn group for speculation on which sequencing platform will deliver a $1K 30X human ...
5 comments:
Tuesday, August 24, 2010

Lawyers v. Research Funding?

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An ongoing personal quest is to attempt to fill in the gaps in my original education, particularly outside the areas of science in which I f...
Saturday, August 21, 2010

Varus! Where are my legions (of data)!?!?

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Bring up the subject of outsourcing, and many minds will immediately jump to the idea of a company using outside services to more cheaply re...
Tuesday, August 17, 2010

Life Tech Gobbles Ion Torrent

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Tonight's big news is that Life Technologies, the giant formed by the merger of ABI and Invitrogen, has acquired Ion Torrent for an eye ...
7 comments:
Saturday, August 07, 2010

Perchance to dream

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I had an amusing dream the other night. Nothing earth shattering: neither starved calves consuming fatted ones nor serpentine molecular orb...
1 comment:
Sunday, August 01, 2010

Curse you Larry the CEO!

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A bit after getting to my current shop, I requested some serious iron for my work and it was decided I would have a Linux box. The question...
8 comments:
Friday, July 30, 2010

A huge scan through cancer genomes

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Genentech and Affymetrix just published a huge paper in Nature using a novel technology to scan 4Mb in 441 tumor genomes for mutations, the ...
1 comment:
Thursday, July 22, 2010

Salespeople, don't forget your props!

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I had lunch today with a friend & former colleague who sells some cool genomics gadgets. One thing I've noted about him is whenever...
5 comments:
Wednesday, July 21, 2010

Distractions -- there's an app for that

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Today I finally gave in to temptation & developed a Hello World application for my Droid. Okay, developed is a gross overstatement -- I...
2 comments:
Tuesday, July 13, 2010

There are 2 styles of Excel reports: Mine & Wrong

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A key discovery which is made by many programmers, both inside and outside bioinformatics, is that Microsoft Excel is very useful as a gener...
3 comments:
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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