Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Friday, July 30, 2010

A huge scan through cancer genomes

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Genentech and Affymetrix just published a huge paper in Nature using a novel technology to scan 4Mb in 441 tumor genomes for mutations, the ...
1 comment:
Thursday, July 22, 2010

Salespeople, don't forget your props!

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I had lunch today with a friend & former colleague who sells some cool genomics gadgets. One thing I've noted about him is whenever...
5 comments:
Wednesday, July 21, 2010

Distractions -- there's an app for that

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Today I finally gave in to temptation & developed a Hello World application for my Droid. Okay, developed is a gross overstatement -- I...
2 comments:
Tuesday, July 13, 2010

There are 2 styles of Excel reports: Mine & Wrong

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A key discovery which is made by many programmers, both inside and outside bioinformatics, is that Microsoft Excel is very useful as a gener...
3 comments:
Monday, June 28, 2010

Knome Cofactors Ozzie Ozbourne's Genome

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I got an email today pointing out that Cofactor Genomics will be responsible for generating Ozzie Osbourne's genome sequence for Knome ....
Sunday, June 27, 2010

Filling a gap in the previous post

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After thinking about my previous entry on PacBio's sample prep and variant sensitivity paper I realized there was a significant gap -- ...
Wednesday, June 23, 2010

PacBio oiBcaP PacBio oiBcaP

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PacBio has a paper in Nucleic Acid Research giving a few more details on sample prep and some limited sequencing quality data on their plat...
1 comment:
Monday, June 07, 2010

What's Gnu in Sequencing?

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The latest company to make a splashy debut is GnuBio, a startup out of Harvard which gave a presentation at the recent Personal Genomics con...
5 comments:
Saturday, June 05, 2010

Trying to Kick the Bullet

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I know the title looks like a malapropism, but it isn't. What I'm trying to do is wean myself away from bulleted lists in PowerPoin...
2 comments:
Monday, May 31, 2010

Sepsis: A Severe Shock

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At the beginning of the weekend I received a real shock: one of the other father's in TNG's Cub Scout Pack had died of sepsis after ...
1 comment:
Tuesday, May 25, 2010

Guesting over at MolBio Research Highlights

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I have an invited piece on the various sequencing instruments over at MolBio Research Highlights . The fact that much of it is an extended...
1 comment:

Bike in the Commuting Fold

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Okay, a little bragging: I biked into to work last week for Bike to Work week. I actually bike the last leg of my commute a lot of days now ...
Saturday, May 22, 2010

Just say no to programming primitivism

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A consistently reappearing thread in any bioinformatics discussion space is "What programming language should I learn/teach?". As...
7 comments:
Thursday, May 20, 2010

The New Genome on the Block

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The world is abuzz with the announcement by Craig Venter and colleagues that they have successfully booted up a synthetic bacterial genome. ...
Tuesday, May 18, 2010

Journey to Atlantis

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I've only seen it a few times, but the sight of the iconic cavernous building always makes my heart race. But this time even more so, a...
3 comments:
Thursday, May 06, 2010

Sales

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Two weeks ago I participated in a roundtable sponsored by the Massachusetts Technology Leadership Council (MassTLC) titled "R&D IT ...
1 comment:
Saturday, May 01, 2010

Asymptotically Approaching A Grok of Scala

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When learning a new language, it is tempting to fall back on the patterns of a previous language. This isn't always a bad thing but is ...
1 comment:
Thursday, April 29, 2010

Application of Second Generation Sequencing to Cancer Genomics

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A review by me titled " Application of Second Generation Sequencing to Cancer Genomics " is now available on the Advance Access se...
Wednesday, April 14, 2010

The value of cancer genomics

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I recently got around to reading the "Human Genome at 10" issue of Nature. One feature, on facing pages, are opinion pieces by Ro...
3 comments:
Thursday, April 08, 2010

Version Control Failure

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Well, it was inevitable. A huge (and expensive) case of confused human genome versions. While the human genome is 10 years old, that was ha...
3 comments:
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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