Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Tuesday, October 06, 2009

Diagramming the Atari Pathway

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Okay, it was an outside speaker at work who planted this seed in my brain, and now I can't shake the image -- but perhaps by writing thi...
1 comment:

Why does PNAS clip their RSS feeds?

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Okay, minor pet peeve. I've pretty much switched over to using Outlook as an RSS reader to keep up with journals of interest. I still ...
2 comments:
Thursday, October 01, 2009

Pondering Polonators

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Standing next to the Polonator like a proud relative is Kevin McCarthy, who leads the Polonator effort at Dover Systems. I had remembered h...
2 comments:
Monday, September 28, 2009

Locking in new functions

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The September 24th Nature came in the mail today and as always with this journal (otherwise I wouldn't pay for it!) is full of interesti...
2 comments:
Friday, September 25, 2009

How many genomes did I just squash?

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Yesterday was a good day for catching up on the literature; not only did I finally get around to the IL28B papers I blogged about yesterday,...
1 comment:
Thursday, September 24, 2009

Unwarranted pessimism on IL28A/B & HCV?

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I finally got around to reading the Nature News & Views article by Iadonato and Katze summarizing and opining on the recent quartet of p...
1 comment:
Wednesday, September 23, 2009

CHI Next-Gen Conference, Day 3 (final)

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Final day of conference, with some serious fatigue setting in (my hotel room was too close to, and faced, a highway. Doh!) Discovered that I...
1 comment:
Tuesday, September 22, 2009

CHI Next-Gen Conference, Day 2

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I'll confess that in the morning I took notes on only one talk, but the afternoon got back into gear. The morning talk was by John Quack...
1 comment:
Monday, September 21, 2009

CHI Next-Gen Conference, Day 1

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Interesting set of talks today. I never did explicitly check on the blogging policy, but given that the session chair kidded a speaker that...
9 comments:
Sunday, September 20, 2009

Next-Generation Sequencing Conference, Providence RI, Day 0

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I'm going to be at Cambridge HealthTech's Next-Gen Sequencing Conference in exotic Providence RI for the next few days. I need to c...
Thursday, September 17, 2009

A genome too far?

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I've crossed fruit flies, tomatoes and yeast, but I would clearly draw the line before taking on this project. A genetic linkage map for...
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Tuesday, September 15, 2009

Industrial Protein Production: Further Thoughts

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A question raised by a commenter on yesterday's piece about codon optimization is how critical is this for the typical molecular biolog...
1 comment:
Monday, September 14, 2009

Codon Optimization is Not Bunk?

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In a previous post I asked " Is Codon Optimization Bunk? ", reflecting on a paper which showed that the typical rules for codon op...
9 comments:
Wednesday, September 09, 2009

A Blight's Genome

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Normally this time of year I would be watching the weather forecasts checking for the dreaded early frost which slays tomato plants, often f...
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Tuesday, September 08, 2009

Next-generation Physical Maps III: HAPPy Maps

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A second paper which triggered my current physical map madness is a piece (open access!) arguing for the adaptation of HAPPY mapping to nex...
Monday, September 07, 2009

Farewell to Summer

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The autumnal equinox is still a few weeks away, but today marks the traditional end of the summer vacation season. How does a genomics geek...
Thursday, September 03, 2009

Physical Maps II: Reading the signposts

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How do we build physical map? In the abstract, a physical map is built by first dividing the genome up into either individual pieces or poo...
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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