Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Thursday, January 17, 2008

Portrait of a scientist

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Judah Folkman's passing this week was a sad event. I got to hear the great man speak -- at Millennium's spectacular internal semina...
2 comments:
Tuesday, January 15, 2008

Watching the returns

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I'm probably going to stay up later than I should tonight watching the returns. Yep, I'm a junkie for the stuff -- it's just so...
Thursday, December 27, 2007

A Vertex by the sea?

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If one thinks like a builder, it is not difficult to scan the prime biotech zone in Cambridge and see it full at some point. I remember bic...
Thursday, December 20, 2007

Getting my hands wet

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My undergraduate days were full of laboratory work. I got involved in student research as an undergraduate, spent a xmemorable summer being...
Monday, December 17, 2007

The Nine Circles of Basel

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Human society has long had a fascination with large human enterprises. Complex governmental systems, with ministers and sub-ministers, seem...
Thursday, December 13, 2007

Corporate DNA

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Hsien-Hsien is frequently asking 'What's in your DNA?', and a correspondent of mine recently pointed out that "it's in...
3 comments:
Monday, December 03, 2007

What Cell Is This, Who Laid To Rest?

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With the holiday season upon us, I break out my seasonal music. So it is only fitting while I ponder various versions of Greensleeves that ...
1 comment:
Sunday, December 02, 2007

Metastasis research deficit?

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The Boston Globe had an article starting on the front page (briefly free, then will require $$) titled 'Critics blast slow progress on...
1 comment:
Wednesday, November 28, 2007

The Incredible Shrinking Human Genome

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When the human genome was still terra incognito (or, at least our knowledge of the sequence was something like my view of the world sans my ...
2 comments:
Tuesday, November 20, 2007

Gene Logic successfully repositions, Ore What?

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Gene Logic today announced that Pfizer has filed a patent based on a Gene Logic drug repositioning effort. This would appear to be one of t...
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Friday, November 16, 2007

Docs eager to winkle wrinkles, slow to hole a mole

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I'm no fan of the local TV news broadcasts & therefore rarely catch them. So it was quite by accident that I caught a story last ni...
1 comment:
Thursday, November 15, 2007

Trapping the wily VEGF

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A significant challenge in pharmacology is the correct dosing of the drug. "The dose makes the poison" is an adage in toxicology,...
1 comment:
Wednesday, November 14, 2007

Ring around the protein...

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One of the journals I monitor by RSS is Nucleic Acids Research, and the usual steady flow of new items has become a torrent, mostly about d...
Monday, November 12, 2007

Just how wrong is Marilyn vos Savant?

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Marilyn vos Savant is a writer of a regular column in Parade magazine. These columns address many things, but often have interesting logic...
12 comments:
Wednesday, November 07, 2007

Can you Flex your DNA?

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One component of many employment benefit packages in the U.S. (I don't know about other countries) is a Medical Flexible Spending Accoun...
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Tuesday, November 06, 2007

Lung Cancer Genomics

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A large lung cancer genomics study has been making a big splash. Using SNP microarrays to look for changes in the copy number of genes acr...
2 comments:
Wednesday, October 31, 2007

Scientific Easter Eggs

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Tonight, of course, is Halloween, one of the many holidays which in the U.S. has a serious sweet tooth. After taking Version 2.0 around for...
1 comment:
Monday, October 29, 2007

One lap around

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Officially, I started this blog a year ago yesterday , with the first post about science coming the next day . At times, I wonder what posse...
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Saturday, October 27, 2007

Genomics Lemonade

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One of the many attractions of the next generation sequencing techniques is that they eliminate the step of cloning in E.coli the DNA to be ...
Thursday, October 25, 2007

At long last, a 2nd GPCR crystal structure

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G-protein coupled receptors, or GPCRs, are a key class of eukaryotic membrane receptors. Roughly 50% of all small molecule therapeutics tar...
2 comments:
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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