Omics! Omics!

A computational biologist's personal views on new technologies & publications on genomics & proteomics and their impact on drug discovery

Wednesday, October 31, 2007

Scientific Easter Eggs

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Tonight, of course, is Halloween, one of the many holidays which in the U.S. has a serious sweet tooth. After taking Version 2.0 around for...
1 comment:
Monday, October 29, 2007

One lap around

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Officially, I started this blog a year ago yesterday , with the first post about science coming the next day . At times, I wonder what posse...
2 comments:
Saturday, October 27, 2007

Genomics Lemonade

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One of the many attractions of the next generation sequencing techniques is that they eliminate the step of cloning in E.coli the DNA to be ...
Thursday, October 25, 2007

At long last, a 2nd GPCR crystal structure

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G-protein coupled receptors, or GPCRs, are a key class of eukaryotic membrane receptors. Roughly 50% of all small molecule therapeutics tar...
2 comments:

Sanguine Thoughts

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Sometimes in life, you just want to lie back and stare at the ceiling. Other times, you have no choice, which is how I found myself for a w...
Friday, October 19, 2007

What do Harry Potter, Sherlock Holmes, Martha's Vineyard & Science Magazine have in common?

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As the Harry Potter series went on, more and more of the characters' names telegraphed a key component of their properties. One of the ...
Thursday, October 18, 2007

Chlamydomonas swims across the line

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Last week's Science contained the p ublication of the Chlamydomonas reinhardtii genome , an old friend of mine from my undergraduate day...
Wednesday, October 17, 2007

When Personal Genomics is Very Personal

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Anyone interested in personal genomics should hunt down the new Nature (available online at the moment) and read the story of Hugh Rienhoff ...
4 comments:
Tuesday, October 16, 2007

Innumeracy at the highest levels

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I admire Richard Branson for his many entrepreneurial and adventuring efforts. I am especially wishing for the success of his spaceflight v...
Monday, October 15, 2007

Nobel Silly Season

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For a number of years now I think of early October as Nobel season. With the prizes often come two rounds of silliness. The fun silliness a...
1 comment:
Friday, October 12, 2007

National Wildlife Genomics

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Visitors to our house are likely to quickly notice a recurrent theme in the decor, starting with a garden ornament and continuing throughout...
1 comment:
Thursday, October 11, 2007

Opus #173, Programming on the Dark Side (C#)

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I had commented a while back that I was contemplating shifting my programming focus from Perl to another language. The existing code base ...
11 comments:

Yet Another Far Out Sequencing Idea?

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GenomeWeb carries the news that another little-known company, this time English, has thrown its hat into the Archon X-Prize ring . Base4 In...
Tuesday, October 09, 2007

This Old Genome

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I recently stumbled across a paper proposing a set of mammalian genomes for sequencing to further aging research. A free version of the pro...
Tuesday, October 02, 2007

Interference Inteference

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A recent publication in Nucleic Acids Research (a very fine journal which is now all open-access) highlights an underappreciated (IMHO) asp...
Monday, October 01, 2007

Spot's Ridges (& Ridge's Spots?)

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Miss Amanda is quite excited about two new papers on the Nature Genetics preprint site, though as we don't have a subscription we're...
1 comment:
Friday, September 28, 2007

A little follow-up

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Sometimes soon after writing something I see something related to the post, but I've been lousy about doing anything about it. But this...

Casting a beady eye on kinases

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A huge area of drug discovery is targeting protein kinases. There are about 500 protein kinase-like proteins in the human proteome. Some o...
2 comments:
Thursday, September 27, 2007

What exactly is Sanger sequencing?

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Today's GenomeWeb contained an item on yet another genome sequencing startup , Genome Corp (which was the name proposed for the first ge...
2 comments:
Tuesday, September 25, 2007

A First Commercial Nanopore Foray?

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Today's GenomeWeb carried the news that Sequenom has licensed a bit of nanopore technology with the intent of developing a DNA sequence...
2 comments:
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Keith Robison
Dr. Robison spent 10 years at Millennium Pharmaceuticals working with various genomics & proteomics technologies & working on multiple teams attempting to apply these throughout the drug discovery process. He spent 2 years at Codon Devices working on a variety of protein & metabolic engineering projects as well as monitoring a high-throughput gene synthesis facility. After a brief bit of consulting, he rejoined the cancer drug discovery field at Infinity Pharmaceuticals in May 2009. In September 2011 he joined Warp Drive Bio, a startup applying genomics to natural product drug discovery. In February 2019 he joined Ginkgo Bioworks, a synthetic biology company. Other recurring characters in this blog are his late loyal Shih Tzu Amanda, his current Shih Poo Lily and his now adult son alias TNG (The Next Generation). Dr. Robison can be reached via his Gmail account, keith.e.robison@gmail.com You can also follow him on Twitter as @OmicsOmicsBlog.
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