tag:blogger.com,1999:blog-36768584.post712561032661346991..comments2024-03-03T18:49:34.382-05:00Comments on Omics! Omics!: Reversible Terminators: Not Just For SequencingKeith Robisonhttp://www.blogger.com/profile/04765318239070312590noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-36768584.post-15361138953118685732020-09-07T23:06:52.166-04:002020-09-07T23:06:52.166-04:00Indeed, I tried to validate this method myself and...Indeed, I tried to validate this method myself and found that deoxyinosine functions as a deoxyguanosine analog and pairs exclusively with deoxycitidine. The paper is deeply flawed.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-36768584.post-91546098969225205672016-12-14T16:39:07.042-05:002016-12-14T16:39:07.042-05:00I had a brief look at the paper. I believe that so...I had a brief look at the paper. I believe that something is wrong, because all polymerases copy a inosine in any template to a C. This has been long established by Kobayashi et al. (http://nass.oxfordjournals.org/content/48/1/225). I have experienced myself that inosine solely encodes for C when copied.<br />I suppose that some controls were missing and a retraction of the patent application will be pending (sic!).Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-36768584.post-77907248180741846252016-12-07T09:43:45.934-05:002016-12-07T09:43:45.934-05:00patents publish 18 months after filing of provisio...patents publish 18 months after filing of provisional application....Anonymousnoreply@blogger.com