tag:blogger.com,1999:blog-36768584.post6076179330540202640..comments2024-03-03T18:49:34.382-05:00Comments on Omics! Omics!: Element Unveils AVITIKeith Robisonhttp://www.blogger.com/profile/04765318239070312590noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-36768584.post-88113926603822585652022-03-24T09:19:10.982-04:002022-03-24T09:19:10.982-04:00I am not a patent attorney, but it would be great ...I am not a patent attorney, but it would be great if somebody could explain how is Element's approach different from Omniome's US 2019 / 0032124 A1, when claim 1 reads:<br /><br />A method of identifying a base in a primed template nucleic acid, comprising<br />(a) contacting a primed template nucleic acid with a polymerase and a test nucleotide, under conditions that:<br />(i) stabilize ternary complex formed between the polymerase, primed template nucleic acid and test nucleotide when the test nucleotide is complementary to the next base of the primed template nucleic acid while precluding incorporation of the test nucleotide into the primer, and<br />(ii) destabilize binary complex formed between the primed template nucleic acid and the polymerase when the test nucleotide is not complementary to the next base of the primed template nucleic acid;<br />(b) detecting the ternary complex while precluding incorporation of the test nucleotide into the primer; and<br />(c) identifying the next base of the primed template nucleic acid from the detected ternary complex.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-36768584.post-36116148694378549852022-03-21T14:42:56.650-04:002022-03-21T14:42:56.650-04:00It will be interesting to see future potential lit...It will be interesting to see future potential litigation with Omniome given the possible overlapAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-36768584.post-27970932328864746462022-03-16T18:26:11.020-04:002022-03-16T18:26:11.020-04:00Based on description, does seem like sequencing by...Based on description, does seem like sequencing by binding. <br />Will be interesting to see if this overlaps with Omniome approach.<br />How do you view the Element vs Singular sequencers? seems like Element value proposition is better? (5$/G vs 15-20$G?)Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-36768584.post-31089596595044277882022-03-15T12:11:12.504-04:002022-03-15T12:11:12.504-04:00it is almost like... sequencing by binding?it is almost like... sequencing by binding?Anonymousnoreply@blogger.com