tag:blogger.com,1999:blog-36768584.post5142104355044913775..comments2024-03-03T18:49:34.382-05:00Comments on Omics! Omics!: BGI Launches the BGISEQ-500Keith Robisonhttp://www.blogger.com/profile/04765318239070312590noreply@blogger.comBlogger1125tag:blogger.com,1999:blog-36768584.post-58647482475588808802015-10-29T04:17:02.589-04:002015-10-29T04:17:02.589-04:00Hi Keith, nice to hear your perspective on BGI'...Hi Keith, nice to hear your perspective on BGI's new benchtop NGS system.<br /><br />On the readlength, a few clarifications that came up while chatting with Radoje Drmnanac. (Believe it or not, after stepping out of a plenary for a prospective partner meeting then hanging out with Suzanne Yokota at the Complete Genomics booth not only was I able to meet Rade but also Maynard Olson.) The Revolocity is 2x28 bp mate-pair, with 375 ave insert length but could go up to 1kb.<br /><br />The BGISEQ-500 as announced is offered as 1x50, 2x50, 1x100 and 2x100 bp readlengths. They have also changed the name of their chemistry from cPAL to cPAS - combinatorial Probe Anchor Synthesis, and a slide (that I wasn't able to capture nor got a translation in the audio as Xu Xun gave the entire presentation in Chinese) made it clear it was polymerase-based, not ligase-based.<br /><br />I've been told since writing up my original post (and should update the original one) is that the system will be priced 1/3 less than 'an equivalent sequencer' which is the NextSeq-500. or about $165K, and the cost of the reagents also 1/3 less. <br /><br />Whereever this technology goes will be interesting, and something to keep a close eye on for sure. Anonymoushttps://www.blogger.com/profile/06793338970769363594noreply@blogger.com