tag:blogger.com,1999:blog-36768584.post1277852739799213147..comments2024-03-03T18:49:34.382-05:00Comments on Omics! Omics!: HelicosTech Back on the Dance Floor?Keith Robisonhttp://www.blogger.com/profile/04765318239070312590noreply@blogger.comBlogger3125tag:blogger.com,1999:blog-36768584.post-29561439656916885822015-11-17T23:47:25.792-05:002015-11-17T23:47:25.792-05:00Using TIRF for NGS isn't new... The original G...Using TIRF for NGS isn't new... The original GA (and it's evolutions) from Illumina are essentially TIRF microscopes.Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-36768584.post-51335907481503921602015-11-01T09:50:42.282-05:002015-11-01T09:50:42.282-05:00Hi Keith, 'what goes around comes around',...Hi Keith, 'what goes around comes around', and with the intersection between methods used to look at protein (I remember reading about TIRF in the early 2000's as it applied to protein sensors) now applied to DNA sequencing technology is an interesting development.<br /><br />This new Helicos approach sure does look interesting, as eliminating library preparation makes a lot of sense for simplifying the workflow. It would seem ideal if cluster generation (or template prep as it is alternatively called) could be combined with library preparation for targeted applications.<br /><br />DaleAnonymoushttps://www.blogger.com/profile/06793338970769363594noreply@blogger.comtag:blogger.com,1999:blog-36768584.post-77273768074497041542015-11-01T08:57:54.610-05:002015-11-01T08:57:54.610-05:00Maybe I can start a hipster trend to bring back Sa...Maybe I can start a hipster trend to bring back Sanger sequencing (the reads just feel much "warmer" and "alive" than NGS stuff). For added cred, maybe I can have the sequencers output the data (analog of course) onto vinyl records.<br />Jonathan Badgerhttps://www.blogger.com/profile/04921990886076027719noreply@blogger.com